![]() Avoid cyclizine in patients with severe heart disease.Intramuscular or intravenous injection, 50mg 3 times daily.Oral, cyclizine hydrochloride 50mg up to 3 times daily.Nausea and vomiting in pregnancy and Hyperemesis Gravidarum ( second line).Nausea, vomiting, vertigo, motion sickness, labyrinthine disorders.Solution for injection 50mg/ml (£1.01 = 1ml amp).Tablets 50mg (£3.25 = 50mg three times a day).Motion sickness, 30mg 2 hours before travel then 15mg every 8 hours during journey if necessary.Vestibular disorders, 30mg 3 times daily.Vestibular disorders, such as vertigo, tinnitus, nausea and vomiting in Ménière's disease.Tablets 15mg (£9.44 = 30mg three times daily).Please click here for further information, exceptions, and a patient leaflet. Some self-care medicines are available from shops and supermarkets. Many of these products are cheap to buy and are readily available OTC along with advice from pharmacies. These conditions include infrequent migraine and travel sickness. NHS England (NHSE) has published new prescribing guidance for various common conditions for which over the counter (OTC) items should not be routinely prescribed in primary care ( quick reference guide). diabetic ketoacidosis, or in excessive digoxin or anti-epileptic dosage. Anti-emetics are unnecessary and sometimes harmful when the cause can be treated e.g. Most antiemetic drugs have antagonist activity at one or more of these receptors.Īnti-emetics should be prescribed only when the cause of vomiting is known, particularly in children, otherwise the symptomatic relief that they produce may delay diagnosis. CTZ activity is modified by a variety of receptors, including histaminic, muscarinic and serotonergic. The vomiting center receives input via the nervous system from many sources, including the chemoreceptor trigger zone (CTZ), the pharynx, the gastrointestinal tract, pain receptors and the vestibular apparatus. Vomiting is a complicated process mediated by a central coordinating 'vomiting center', which is located in the brain stem. Levomepromazine (see 4.2 Drugs used in psychoses and related disorders).Promethazine (see 3.4.1 Antihistamines).Lorazepam (see section 4.8 Antiepileptic drugs).Haloperidol (see 4.3 Antidepressant drugs).4.13 Miscellaneous nervous system preparationsĭrugs used for nausea and labyrinth disorders not listed below:.4.10 Drugs used in substance dependence.4.9 Drugs used in parkinsonism and related disorders.4.5 Drugs used in the treatment of obesity.4.4 CNS stimulants and drugs for attention deficit hyperactivity disorder.4.2 Drugs used in psychoses and related disorders.Treatment of schizophrenia and related psychoses.Management of behavioural and psychological symptoms of dementia (BPSD).Treatment of anxiety spectrum and related disorders.Management of low back pain and sciatica.Management of pain in substance misuse disorders.
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